Most multivitamins are designed for a general population with average nutritional needs. Everyday Support was designed with a specific population in mind: women with lipedema, many of whom are following restrictive eating plans, dealing with gut inflammation that may impair absorption, and carrying genetic variants that affect how they process certain nutrients.
It is the product Dr. Jonie is most personally invested in, and the formulation decisions behind it reflect years of clinical observation about what this specific group of women is consistently missing.
Why standard multivitamins may fall short
Women with lipedema face a convergence of factors that can drive nutritional deficiency. Gut inflammation may reduce absorption of fat-soluble vitamins and minerals even when dietary intake is adequate. Low-carbohydrate and ketogenic diets, which are among the most clinically supported eating approaches for lipedema, eliminate many fortified grain products that conventionally contribute to B vitamin intake. A long history of restrictive dieting, which applies to nearly every woman with lipedema, can compound deficiency over time.
Add to that the methylenetetrahydrofolate reductase (MTHFR) factor. A significant number of women with lipedema carry variants of the MTHFR gene that affect the body's ability to convert standard B vitamins into their usable methylated form. A woman with an MTHFR variant who takes regular folic acid or B12 may see it show up in a blood test but still be functionally deficient because her body cannot use what it has. Everyday Support uses methylated B vitamins specifically to address this, bypassing the conversion step entirely.
What's in it and why
The formulation covers the deficiency pattern most consistently seen in this population: methylated B vitamins including B12 and folate, thiamine for anyone with a history of bariatric surgery or very low-calorie dieting, vitamin D, selenium for thyroid and immune support, and zinc. Each was chosen based on both the general evidence for deficiency in lipedema and the specific dietary context of the women most likely to use it.
What to expect
Most women notice improved energy and reduced fatigue within the first few weeks, particularly from the methylated B vitamins. For women who have been unknowingly deficient in B12 or folate for an extended period, the shift can be noticeable.
Dr. Jonie recommends taking Everyday Support in the morning. The energy-supporting properties of methylated B vitamins can occasionally make it harder to sleep if taken later in the day.
Find Lipé Everyday Support at lipedemasupplements.com